Sen. Joe Manchin (D-W.Va.) is not on the ballot in November.

But that isnt stopping many Democratic Senate candidates from effectively running against him in competitive primaries.

Whether attacking Manchin on Twitter, invoking his name to raise money, or accusing rivals of resembling the conservative Democratic senator, Manchins prominence in key intraparty contests attests to how much of a villain he has become to Democratic primary voters.

Along with Arizona Sen. Kyrsten Sinema (D), Manchin has been scorned by Democrats for blocking President Joe Bidens key priorities, including the Build Back Better social spending and climate bill, and a filibuster carve-out for voting rights legislation.

Its definitely effective for fundraising and ginning up the activist base, Mike Mikus, a Pittsburgh-based Democratic consultant said. The only open question is: Does it have electoral success? Thats something well find out as the primaries progress.

Mikus said hes never seen Democratic Senate primaries pick up so much steam from attacks against a Democrat from another state. There used to be more conservative Democrats like Manchin, Mikus said, making it harder to train anger on a single person.

In Pennsylvania, three Democrats are vying for the chance to succeed retiring GOP Sen. Pat Toomey: U.S. Rep. Conor Lamb, state Rep. Malcolm Kenyatta, and Lt. Gov. John Fetterman.

Fetterman and Kenyatta, who are both running to Lambs left, have targeted Manchin in fundraising emails and social media posts.

Fetterman has issued five press releases blasting Manchin and has invoked Manchin in at least seven fundraising emails. He even penned a CNN op-ed in June calling Manchin out for refusing to support a filibuster exception for voting rights and election integrity legislation designed to avoid another Jan. 6-style effort to overturn a presidential election.

Some Democrats , like Manchin, who are refusing to reform the filibuster are telling us that allegiance to a flawed Senate rule is more important to them than democracy itself, Fetterman wrote.

Kenyatta has dinged Manchin 14 times on Twitter since April, questioning everything from his commitment to working families and the Democratic Party to his support for preserving democracy itself.

Theres no excuse for defending a Jim Crow era relic, Kenyatta tweeted in June, referring to Manchins support for the filibuster. Sen. Manchin is pissing away the best chance we have to preserve our Democracy and for what?

Lamb, who is running as a mainstream moderate, has broken with Manchin on the core issues. An ally of organized labor who backs expanding Social Security, Lamb voted for the Build Back Better bill that Manchin is obstructing and supports eliminating the filibuster altogether. In a January fundraising email, Lamb lamented how Senate Republicans and two Democrats Manchin and Sinema had used the filibuster to block a vote on voting rights legislation, asking for support so he could use his seat to eliminate the filibuster and advance the legislation.

Across the border in Ohio, Rep. Tim Ryan, the moderate favorite in the Democratic Senate primary, and attorney Morgan Harper, a progressive upstart, have both tried to lay claim to the anti-Manchin mantle.

Ryan, who voted for Build Back Better in the House, has blasted Manchin and Sinema for holding up the multifaceted budget legislation in fundraising emails , on Twitter , in the media , and even in Facebook ads . And like virtually every Democrat running in a competitive Senate race, he supports repealing the filibuster.

Harper has been even more outspoken in her frustrations with Manchin, quipping that she voted for Joe Biden , not Joe Manchin.

In Wisconsin, state Treasurer Sarah Godlewski, the EMILYs List candidate in the race to oust GOP Sen. Ron Johnson, has been the most vocal in recent months among her competitors about her opposition to Manchin. Shes put out statements decrying Manchin and Sinema for slow-rolling negotiations on Build Back Better, and pointed fingers at Manchin in local newspaper interviews for being the reason Wisconsinites cant access paid leave.

Republicans and some Democrats like Manchin and Sinema are blocking important legislation that would help millions of Americans because they are more beholden to special interests than they are to the American people, Godlewski told HuffPost in a statement. She said she hears from voters all the time about the senators obstructionism, including on her recent tour of Wisconsins rural districts a sign that the frustration isnt just concentrated in the states liberal strongholds.

I hear from people every day who are frustrated that any one senator has the power to stand in the way of the things that would make their lives better, said Lt. Gov. Mandela Barnes, a leading candidate in the Democratic Senate race who has been endorsed by Sens. Elizabeth Warren (Mass.) and Cory Booker (N.J.).

Tom Nelson, executive of Outagamie County, who is running for the Senate nomination as a populist with traction in rural parts of the state, has gone so far as to compare Manchin and Sinema with Johnson, the extremist Republican incumbent.

Sinema and Manchin and Johnson. What do they all have in common? They wouldnt step up to protect our democracy, Nelson wrote in a January tweet soliciting online donations.

Manchin has become so toxic in primaries that any ties to him have become a vulnerability for some moderate Democrats even when rival candidates are not openly using it against them.

In Ohio, progressive candidate Harper is casting doubt on where Ryan stands on the Democratic agenda because his campaign accepted a $5,000 contribution from Manchins PAC, Country Roads , which has received major support from corporations opposed to key elements of Build Back Better. In a statement on Friday, Harper tied Ryans receipt of donations from Manchin to his refusal to disavow direct contributions from corporate PACs.

This is just one more way for Tim Ryan to accept corporate cash, Harper said. Manchins PAC is funded by Republicans, big banks, and defense contractors. How can we trust Ryan to act in Ohios best interest when this is who funds his campaigns?